The world already knows that Jorge Moll is one of the most prolific and persistent research leaders today in the field of cognitive neuroscience. However, what makes him even more popular and well-cited in many research papers is the fact that in November 2015 he was able to present a convincing set of results for JAMA Psychiatry about the dynamics behind self-blame-selective hyperconnectivity. In his particular study, he found a link between anterior temporal and subgenual cortices and how it can present a prediction for depressive episodes.
In the study’s abstract, it was argued that many patients suffering from Major Depressive Disorder (MDD) had already previously shown signs of abnormality in their functional magnetic resonance imaging connectivity (fMRI) between the subgenual cingulate cortex and adjacent septal region (SCSR), and the right superior anterior temporal lobe (RSATL). All of these elements have a substantial contribution to how likely a specialist can detect a tendency of patients to aggravate their state of depression.
The remarkable thing about this particular study of Jorge Moll is in the fact that it can provide a robust neural signature that is the foundation of overgeneralized self-blaming emotions. With such results, it is now more likely for a physician to find a risk of recurrence for depression and for establishing a benchmark for prognostic biomarkers that can help in the treatment. We should also indicate here that the study also resulted in confirming the hypothesis that RSATL-SCSR connectivity can predict risk of subsequent recurrence of primary depressive disorder symptoms.
Jorge Moll’s Involvement
It’s not an exaggeration to state here that Jorge Moll, Director of D’Or Institute for Research and Education (IDOR), has played an invaluable role in the study above, along with other remarkable research studies. In 2005, his study on the neural basis of moral cognition had gained about 925 citations, while in 2006, his work on human frontal-mesolimbic networks gained about 821 quotations. All of this is a strong indication of Mr. Moll’s dedication in cognitive neuroscience and in the passionate search for remedies of social behavior ailments.